David de Gea – Anders Lindegaard is perhaps more likely to get his promised game time from David Moyes in next week’s League Cup tie rather than in this Champions League clash.
Rafael – The enthusiastic right-back provides a balance and attacking threat in his position that no-one else at the club can match.
Chris Smalling – Injuries to Rio Ferdinand and Nemanja Vidic mean Moyes will have to his young central defenders on Wednesday, with Smalling certainly in contention after only being a substitute at the weekend.
Jonny Evans – The Northern Irishman is considered by many to now be United’s best central defender and should have another chance to prove those claims on Wednesday night.
Patrice Evra – Some confusing comments have hinted that this may be Evra’s last season at United and he will be missed if that is true. He brings an important attacking dimension to United’s forward play.
Antonio Valencia – After missing out at the weekend, the Ecuadorian is expected to start on the right side of midfield against Real Sociedad.
Phil Jones – Jones may well be given the opportunity to partner Carrick on Wednesday. He will need to offer energy and dynamism to a sometimes static central midfield.
Shinji Kagawa – A rare start for Kagawa may be on the cards as Moyes looks to give the Japanese player opportunities. The Champions League would appear to be the perfect stage for Kagawa.
Wayne Rooney – Rooney, a player who rarely needs rest, can be expected to start again against Real Sociedad.
Javier Hernandez – Moyes has hinted at upcoming opportunities for the Mexican striker and with Welbeck injured and Van Persie only just recovering from a knock to play last weekend, this could be the ideal chance to start Chicharito.
The potential inclusion of Kagawa hints at a more fluid attacking quarter with Rooney and him floating behind the striker and to the left. Hernandez will sit on the last man and trouble the defence with his trademark runs.
A line-up such as this would be most similar to how United set-up earlier in the season against Leverkusen which turned to be a very exciting game. It would also be on average an extremely young team and a signal of intent from Moyes about the hopes he has for the future.