De Gea; Rafael, Smalling, Vidic, Evra; Valencia, Cleverley, Carrick, Mata; Rooney, Van Persie
Lindegaard, Büttner, Ferdinand, Fellaini, Young, Hernandez, Januzaj
David Moyes has made a few changes to the side that lost to Fulham at the weekend.
Tom Cleverley and Antonio Valencia come in for Darren Fletcher and Ashley Young while Juan Mata, Wayne Rooney and Robin van Persie all start again in the attack.
Adnan Januzaj has to settle for a place on the bench. Phil Jones has clearly not recovered in time to make the squad while there is no space for Darren Fletcher and Shinji Kagawa.
It looks like 4-4-2 again.