David de Gea – De Gea continues to be the most obvious name on the teamsheet.
Rafael – It was good to see Rafael return to action last weekend and he is set to start ahead of Antonio Valencia at right-back.
Jonny Evans – Evans should start ahead of Chris Smalling who has only just returned to fitness.
Tyler Blackett – Blackett continues to impress and will get another chance to shine on Sunday.
Marcus Rojo – A good display last weekend means Rojo is set to get the nod at left-back ahead of Luke Shaw.
Daley Blind – Blind is likely to start in favour of Darren Fletcher in a deep-lying midfield role.
Ander Herrera – One of United’s men of the match last weekend will be hoping to cement his midfield place with continued impressive performances.
Angel di Maria – The Argentine is a no-brainer for Sunday.
Juan Mata – After a goal and decent performance last weekend, Mata is likely to continue for now in the No.10 role but in such a competitive position he will need to put in another good display.
Wayne Rooney – It would be a surprise to United’s captain dropped.
It is expected that Van Gaal will continue with the diamond formation after it proved so successful against QPR. It appears to be the most obvious choice of set-up considering the players United have available.