Shaw suffered a double fracture of his right leg thanks to a terrible tackle from PSV’s Hector Moreno.
The youngster underwent surgery in Eindhoven hours after the game and he will now return to Manchester.
Pochettino, who managed Shaw at Southampton, expressed his sympathy for the player.
“It’s always difficult because he was crying, which is normal. You can understand after a big injury, not only for the pain but everything to do with the situation. It’s always a difficult moment for a player,” Pochettino said.
“He is much better today but I feel very sorry for him. It had a big impact on me. I watched the moment happen and I felt sick after I saw it. I can I can only give my support and wish a speedy recovery but now it’s about thinking of recovery as soon as possible after his injury.
“It was never the intention of Hector Moreno to do this but that is football. There is always danger and sometimes this kind of thing happens. It was unlucky for Luke.”
Figures from across the sporting world have united in their support for Shaw, which goes to show just how much of a likeable character he is. The 20-year-old reportedly faces at least six months on the sidelines and the hope for United fans is that he can feature in the later stages of the season as he had made a brilliant start to the campaign.