Wilson made his first Premier League appearance in the 3-0 loss to Arsenal but it’s unfortunate that he’s now back out of the squad with illness.
Romero and Valencia have returned to the team and it gives van Gaal options just in case anything happens ahead of kick-off.
“Willo was a little bit ill – Wilson as he is named but, for us, it is Willo – so he shall not travel with us.
“I’ll take 20 players with me. It’s a four-hour flight so, if a player gets ill, I have the other player in my environment.
“Of course that was the reason [Romero and Valencia were absent at Everton]. They have to cope with the jet-lag so I didn’t think it was wise to take them with us against Everton.”
A round-trip to Moscow is the worst possible preparation for a home game against Manchester City at the weekend but it’s something United have to deal with.
What will be interesting is to see whether van Gaal will rotate a lot of his players in order to keep them fresh for the derby.