Manchester United: Romero; Varela, Carrick, Blind, Riley; Schneiderlin, Ander Herrera; Lingard, Mata, Memphis; Martial
Subs: J.Pereira, Rojo, Poole, McNair, Love, A.Pereira, Rashford
Riley comes in for the injured Cameron Borthwick-Jackson, who picked up a complaint in the FA Cup win at Shrewsbury last time out. Michael Carrick also lines up in defence in the absence of Chris Smalling.
Andreas Pereira can only make the substitute’s bench despite his encouraging cameo against Shrewsbury.
He is joined by Marcus Rashford, who has impressed in the academy teams but is yet to make his senior debut. It is crucial that United advance in Europe and supporters will be looking for a convincing win against Midtjylland following the 2-1 loss against the Danish outfit in the first leg.