The 25-man pre-season squad was announced on Tuesday morning, with the first game taking place on July 22 against Borussia Dortmund in Shanghai.
Borthwick-Jackson endeared himself to Man United supporters following a series of promising performances under Louis van Gaal last season, making ten appearances in total.
The 19-year-old is expected to be available for selection against Leicester City on August 7, but will not travel to China.
Missing pre-season, the ideal time for youngsters to showcase their ability to a new manager, will be a significant blow for the Englishman. It could be the difference between a fruitful spell in the first-team and anonymity.
However, despite missing his chance to impress before the 2016/17 campaign begins, Borthwick-Jackson can be positive about his future prospects.
His performances last year were hallmarked by poise, composure, intelligence and a surprisingly dangerous cross from the left hand side. That mixture of solidity and creativity would not have been ignored by the Portuguese boss, who clearly regards the 19-year-old as a bright prospect. The almost immediate offer of a new contract to the youngster upon his arrival to Old Trafford provides good reason to believe that United fans will see more of Borthwick-Jackson next year.